An “Arbor Day.”

Shopping in Ann Arbor

Determinants of synaptic strength vary across an axon arbor.

We used synaptophysin-pHluorin expressed in hippocampal neurons to address how functional properties of terminals, namely, evoked release, total vesicle pool size, and release fraction, vary spatially across individual axon arbors. Consistent with previous reports, over short arbor distances (≈ 100 μm), evoked release was spatially heterogeneous when terminals contacted different postsynaptic d...

Diabetes Dictating Policy: An Editorial Commemorating World Health Day 2016

The 21st century is an era of great challenge for humankind; we are combating terrorism, climate change, poverty, human rights issues and last but not least non-communicable diseases (NCDs). The burden of the latter has become so large that it is being recognized by world leaders globally as an area that it is in need of much greater attention. In light of this concern, the World Health Organiz...

An apple a day ...

To store apples, refrigerate them in a plastic bag or in the crisper drawer. Check the stored apples often – one bad apple can spoil the whole bag! When you cut a raw apple, it may turn dark. To prevent this, dip the pieces in a fruit juice like lemon, orange, grapefruit, or pineapple before combining with other ingredients. Right now, apples are in pretty good supply. Whether you buy locally g...

One dendritic arbor, two modes of integration.

Editor's Note: These short reviews of a recent paper in the Journal, written exclusively by graduate students or postdoctoral fellows, are intended to mimic the journal clubs that exist in your own departments or institutions. For more information on the format and purpose of the Journal Club, please see